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[New product ] FT3, FT4

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FT3 and FT4 are the English abbreviations for serum free triiodothyronine and serum free thyroxine, respectively.

FT3 and FT4 are the most sensitive indicators for the diagnosis of hyperthyroidism.

Because their content is not affected by thyroid binding globulin, they have important application value in the diagnosis of hyperthyroidism and hypothyroidism, the evaluation of the severity of the disease, and the monitoring of therapeutic effects.

The determination of serum or plasma levels of Triiodothyronine (T3) is recognized as an important measurement in the assessment of thyroid function. Its effects on target tissues are roughly four times more potent than those of T4. Free T3 (FT3) is the unbound and biologically active form, which represents only 0.2‐0.4 % of the total T3.

The determination of free T3 has the advantage of being independent of changes in the concentrations and binding properties of the binding proteins; Therefore free T3 is a useful tool in clinical routine diagnostics for the assessment of the thyroid status. Free T3 measurements support the differential diagnosis of thyroid disorders, are needed to distinguish different forms of hyperthyroidism, and to identify patients with T3 thyrotoxicosis.

The determination of serum or plasma levels of Thyroxine (T4) is recognized as an important measurement in the assessment of thyroid function. Thyroxine (T4) is one of two major hormones produced by the thyroid gland (the other is called triiodothyronine, or T3), T4 and T3 are regulated by a sensitive feedback system involving the hypothalamus and the pituitary gland.

Free T4 is measured together with TSH when thyroid function disorders are suspected. The determination of fT4 is also suitable for monitoring thyrosuppressive therapy.The determination of free T4 has the advantage of being independent of changes in the concentrations and binding properties of the binding proteins;

The content of FT3 is of great significance in the differential diagnosis of whether thyroid function is normal, hyperthyroid or hypothyroid. It is very sensitive to the diagnosis of hyperthyroidism and is a specific indicator for the diagnosis of T3 hyperthyroidism.

FT4 determination is an important part of clinical routine diagnosis and can be used as a monitoring method for thyroid suppression therapy. When thyroid dysfunction is suspected, FT4 and TSH are often measured together.


Post time: Nov-12-2021