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IL-6

Interleukin-6

  • Identify organ transplant rejection
  • Evaluate the efficacy of organ transplantation
  • Increase:Body injury
  • Inflammation
  • Malignant tumors of the digestive tract,etc.

Product Detail

Product Tags

Performance Characteristics

Performance Characteristics

Detection Limit:  1.5 pg/mL;

Linear Range:  3.0-4000.0 pg/mL;

Linear correlation coefficient R ≥ 0.990;       

Precision: within batch C.V. is ≤ 15%; between batches C.V. is ≤ 20%;                         

Accuracy: the relative deviation of the measurement results shall not exceed ± 15% when the accuracy calibrator prepared by IL-6 national standard or standardized accuracy calibrator are tested.

Storage And Stability

1. Store the detector buffer at 2~30℃. The buffer is stable up to 18 months.

2. Store Aehealth Ferritin Rapid Quantitative test cassette at 2~30℃, shelf life is up to 18 months.

3. Test cassette should be used within 1 hour after opening the pack.

Interleukin-6 is a polypeptide. IL-6 is composed of two glycoprotein chains with a molecular weight of 130kd. Interleukin-6 (IL-6) is an important member of the cytokine network and plays a central role in acute inflammation. Induces the acute phase response of the liver and stimulates the production of C-reactive protein (CRP) and fibrinogen. A variety of infectious diseases can lead to increased serum IL-6 levels, and IL-6 levels are closely related to patient prognosis. IL-6 is a pleiotropic cytokine with a wide range of functions, which is secreted by T cells, B cells, monocytes and macrophages and endothelial cells after the body is stimulated by inflammation. It is a key component of the inflammatory mediator network. After the inflammatory reaction occurs, IL-6 is the first to be produced, and after it is produced, it induces the production of CRP and procalcitonin (PCT). Such as acute inflammation in the process of infection, internal and external injuries, surgery, stress response, brain death, tumor production and other conditions will occur rapidly. IL-6 participates in the occurrence and development of many diseases, and its blood level is closely related to inflammation, viral infections, and autoimmune diseases. It changes earlier than CRP. Studies have shown that IL-6 increases rapidly after bacterial infection, PCT increases after 2h, and CRP increases rapidly after 6h. Abnormal IL-6 secretion or gene expression can often lead to a series of diseases. Under pathological conditions, IL-6 can be secreted into the blood circulation in large quantities. The detection of IL-6 is very important for understanding the condition and judging the prognosis.


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